Medarex Announces Presentations At The 33rd Congress Of The European Society For Medical Oncology

�Medarex, Inc.
(Nasdaq: MEDX) announced that nine clinical abstracts for ipilimumab,
an investigational anti-CTLA-4 antibody, in melanoma ar scheduled to be
the subject of presentations at the thirty-third Congress of the European Society
for Medical Oncology (ESMO) being held September 12-16, 2008 in Stockholm.
Many of the following abstracts will include updated one-year selection data
from three Phase 2 studies (008, 022 and 007) in antecedently treated
patients with in advance metastatic melanoma:

Ipilimumab Presentations in Advanced Melanoma



-- "Efficacy and safety of patients with ripe melanoma treated with
ipilimumab with or without the addition of prophylactic budesonide"
(Abstract #783P) I. Ron - Poster presentation from 12:45 p.m. to 1:45 p.m.
local time on Saturday, September 13, 2008.



-- "Treatment guidelines for the management of immune-related adverse
events in patients treated with ipilimumab, an anti-CTLA4 therapy"
(Abstract #787P) K. Chin - Poster discussion from 12:45 p.m. to 1:45 p.m.
local time on Saturday, September 13, 2008.



-- "Ipilimumab-mediated patterns of response in patients with
pretreated, advanced melanoma" (Abstract #784P) K. Harmankaya - Poster
demonstration from 12:45 p.m. to 1:45 p.m. local fourth dimension on Saturday, September
13, 2008.



-- "Clinical activity of ipilimumab in patients with sophisticated melanoma
and brain metastases" (Abstract #786P) J. S. Weber - Poster display
from 12:45 p.m. to 1:45 p.m. local fourth dimension on Saturday, September 13, 2008.



-- "Ipilimumab 10 mg/kg initiation dosing promotes T-cell activating in
patients with advanced melanoma" (Abstract #785P) A. Hoos - Poster
display and treatment from 12:45 p.m. to 1:45 p.m. local time on
Saturday, September 13, 2008.


-- "Effect of dose on efficacy and safety in ipilimumab-treated
patients with advanced melanoma - results from a Phase 2, randomized,
dose-ranging study" (Abstract #769O) C. Lebbe - Oral presentation from 3:30
p.m. to 5:30 p.m. local time on Monday, September 15, 2008.



-- "Efficacy and base hit of treatment-naive and antecedently treated
patients with sophisticated melanoma receiving ipilimumab" (Abstract #778PD) R.
Ridolfi - Poster discussion from 12:30 p.m. to 1:30 p.m. local time on
Monday, September 15, 2008.



-- "Efficacy and safety of ipilimumab in patients with advanced
malignant melanoma who had progressed on one or more prior therapies: results from a
single-arm, multicenter study" (Abstract #776PD) M. Maio - Poster
discourse from 12:30 p.m. to 1:30 p.m. local time on Monday, September 15,
2008.



-- "Prolonged stable disease in ipilimumab-treated patients with
advanced melanoma world Health Organization have progressed on prior anticancer therapies"
(Abstract #768O) V. Chiarion Sileni - Oral presentation from 3:30 p.m. to
5:30 p.m. local time on Monday, September 15, 2008.



More information most the ESMO Congress whitethorn be institute at http://www.esmo.org.

About Medarex



Medarex is a biopharmaceutical company focused on the breakthrough,
development and potential commercialisation of fully human antibody-based
therapeutics to treat severe and debilitating diseases, including
cancer, kindling, autoimmune disorders and infective diseases. Medarex
applies its UltiMAb(R) technology and product development and clinical
manufacture experience to generate, support and potentially commercialize
a broad range of in full human antibody product candidates for itself and its
partners. More than 40 of these therapeutic production candidates derived from
Medarex technology are in human clinical testing or let had INDs submitted
for such trials, with seven of the most advanced product candidates
currently in Phase 3 clinical trials or the subject of regulatory
applications for merchandising authorization. Medarex is committed to construction
value by developing a diverse pipeline of antibody products to address the
world's unmet healthcare needs. For more information around Medarex, visit
its site at http://www.medarex.com.

Medarex(R), the Medarex logo and UltiMAb(R) are registered trademarks
of Medarex, Inc. All rights ar reserved.


Medarex, Inc.
http://www.medarex.com



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Study Indicates Higher Incidence Of Childbirth-Related PTSD Than Previously Thought

�Nearly unrivaled in 10 U.S. women who have given birth recently meet the formal criteria for post-traumatic stress disorder resulting from childbearing, according to a survey released this week by the nonprofit maternity care group Childbirth Connection, the Wall Street Journal reports. Some aesculapian experts say that PTSD, most commonly linked to people wHO have experienced violent events, can as well be triggered by a painful or complicated labor and delivery in which a woman believes she or her child power die. PTSD can congeal in immediately or months after a traumatic event. According to the Journal, the condition often occurs when somebody has experient an event that includes actual or threatened sober injury or death and evokes intense fear or a intuitive feeling of helplessness. Symptoms of the experimental condition can include anxiety, flashbacks and a "numbness to daily life sentence," the Journal reports.

For the survey, titled "New Mothers Speak Out," Childbirth Connection commissioned Harris Interactive to screen 900 U.S. mothers using an established PSTD screening instrument. Nine percent of the women surveyed screened positive for all the criteria of PTSD outlined in the Diagnostic and Statistical Manual of Mental Disorders, and 18% of participants showed some signs of the condition, according to the theme. Researchers renowned that most women enrolled in the survey wHO experienced PTSD and other depression symptoms did non seek professional help. According to the Journal, the rate of PTSD among mothers has not been studied extensively, but separate studies conducted outside the U.S. estimated that betwixt 1.5% and 5.9% of mothers experience the condition. PTSD is thought to be far less vernacular in mothers than postpartum depression, which affects roughly 15% of mothers, according to the National Institute of Mental Health.

Health precaution providers trust the increasing number of obstetric procedures used in labor and delivery could be playing a role in PTSD. Cheryl Beck -- a professor at the University of Connecticut School of Nursing, world Health Organization served as an consultant for the study -- said the mothers reportage signs of PTSD had a higher rate of medical intervention and were more likely to draw feeling helpless in a threatening environment. A history of sexual abuse or other injury also potty increase a woman's danger of experiencing PTSD related to vaginal birth, the Journal reports.

According to the Journal, the survey's results ar "likely to add fuel to a debate roughly how to better key out and process maternal mode disorders and whether widespread, systemic screening is warranted." New Jersey in 2006 passed a law requiring women to be screened for hazard of low after existence discharged following childbirth, as well as at the first postnatal doctor's visit. Other states, including Illinois and Texas, have passed laws to increase educational awareness of postpartum mental conditions.

Federal legislation (S 1375) that would fund research into postpartum mood disorders and the effects of covering for the conditions failed to make the Senate floor last�month as voice of a legislative packet (S 3297), but supporters believe the bill could be reconsidered in the fall. Opponents of the measure have said the bill could lead to increased "drugging of mothers." Shari Lusskin, director of reproductive psychological medicine at New York University Medical Center, said many aspects of PTSD ar not full understood, specially childbirth-related PTSD. She aforementioned, "We don't want to overmedicalize a normal section of human development. Just because you had a traumatic nascency, doesn't bastardly you'll get PTSD" (Zimmerman, Wall Street Journal, 8/5).


Reprinted with kind permission from hTTP://www.nationalpartnership.org. You can persuasion the entire Daily Women's Health Policy Report, lookup the archives, or sign up for email manner of speaking here. The Daily Women's Health Policy Report is published by the National Partnership for Women and families.

� 2007 National Partnership for Women & Families. All rights reserved.


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Lykke Li U.S. Live Dates Announced

Sweden's Lykke Li has mapped-out live dates in North America, with dates set to be held in August, October and November.

These ten performances coincide with the release of 'Youth Novels' - her debut album, that will finally see the light of day in the U.S. on August 19th, via her own label LL Recordings.

Lykke Li released the LP in the UK last month and you can read our review here, and watch a video for lead single 'I'm Good, I'm Gone' here.

August Dates:

Los Angeles, CA Hotel Caf� (25)

New York, NY Le Poisson Rouge (28)

October Dates:

Washington, DC Black Cat (19)

Boston, MA Paradise (23)

Toronto, ON Mod Club (24)

Chicago, IL Empty Bottle (25)

Vancouver, BC Richards on Richards (28)

Seattle, WA Neumo's (29)

Portland, OR Doug Fir (30)

November Dates:

San Francisco, CA Independent (1)

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Radiohead blast EMI over release of ‘Greatest Hits’ album

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The rockers’ contract with the label ended last year; and they decided to giveaway their current album, ‘In Rainbows’, as a free download before releasing it with XL, the same label who had also put out Yorke’s 2006 solo album ‘The Eraser’.

Says Yorke, “We haven’t really had any hits so what exactly is the purpose?

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Vaughn

   
Artist: Vaughn

   Genre(s): 
Rock
   

---

Discography:


   
 Fearless

   Year: 2004   
Tracks: 9

---

 





Kate Hudson - Hudson Doing Well After Wilson Split

Friend believes Ledger was anxious

A close friend of the late Australian actor Heath Ledger has said that he was anxious over the Christmas holidays about not seeing enough of his two-year-old daughter and his split with actress Michelle Williams.
The 28-year-old actor was found dead at his New York apartment on Tuesday; results of an autopsy conducted yesterday were inconclusive.
Reuters reports that in an interview with the West Australian newspaper, model Sophie Ward said that Ledger was worried about his split with actress Michelle Williams and their daughter Matilda during his Christmas holidays at home in Perth.
During the interview, Ward said: "We went to the movies and just did normal stuff... but he was a bit edgy. He couldn't really relax."
She continued: "He said he was going to London but was quite upset because he couldn't see his daughter as much as he'd like to. He was travelling so much and I think he was just frustrated with it all."
"He was clean and wasn't drinking any alcohol or taking drugs," said the model.
She added: "He smoked cigarettes, but that's about it. He was drinking diet Coke when we were together and he said he was very committed to not drinking alcohol. I don't believe he took his own life deliberately."
Police are treating Ledger's death as possibly drug-related and said sleeping pills were found close to his body.
But a spokeswoman for the medical examiner's office said on Wednesday that an autopsy had proved inconclusive and further tests were needed - which could take around 10 days.
The West Australian newspaper says that before Ledger returned to the US from Perth, he left a message with the film editor of the newspaper, thanking the media for leaving him alone.
He said: "I don't know whether it's a conscious thing or an unconscious thing, giving me space and respecting my privacy. It's just been awesome."
He continued: "I've had the most beautiful time back here and being able to see all my friends and family ... It's really enabled me to be a boy again from home and feel like I'd never left. It's truly been an incredibly therapeutic and a much-needed trip home..."
To view a special gallery on the life and career of Heath Ledger, click here.

Fimbulwinter

   
Artist: Fimbulwinter

   Genre(s): 
Metal
   

---

Discography:


   
 Servants of Sorcery

   Year: 1994   
Tracks: 7

---

 





Shania Twain - Shania Twain And Music Producer Husband Split

Shakira, other Latin American stars sing for their cause -- ALAS

Shakira, other Latin American stars sing for their cause -- ALAS

MEXICO City -- Not so long ago, Latin American artists wHO rundle up for mixer causes oft risked prison, exile or far worse.

What a difference a generation makes. On Thursday, a phalanx of Spanish-speaking bulge artists headed by Colombian maven Shakira and Spanish-Italian isaac Bashevis Singer Miguel Bosé gathered here to advertise a fresh initiative to aid Latin America's millions of poor people, malnourished and undereducated children. They were joined by the world's second-richest military personnel, a whirligig U.S. philanthropist and an international rabble of reporters drawn by a potent cocktail of celebrity, money and force, laced with an emerging social conscience.

Swathed in showbiz glamor, the philanthropic-promotional project testament culminate this afternoon with deuce free all-star concerts, ace in the Zócalo, or massive exchange plaza, of the Mexican capital, the other in the Costanera Sur, an ecological reserve on the edge of business district Buenos Aires.





"What's rattling inspiring is to see Latin United States of America for the first time in charge of its own issues," said Shakira, the polyglot 31-year-old chanteuse world Health Organization for years has helped children through her possess Barefooted Foundation garment and of late has been safekeeping caller with the likes of British people Prime Diplomatic minister Gordon Brown and World Bank Prexy Henry Martyn Robert B. Zoellick.

She'll perform in Buenos Aires as contribution of a roster that is supposed to include Alejandro Sanz, Calle 13, Gustavo Cerati, Paulina Rubio and Jorge Drexler. The United Mexican States City card lists Aleks Syntek, Juanes, Los Tigres del Norte, Maná, Babasonicos, Diego Torres, Ricky Martin and Tania Libertad.

Today's concerts, the most high profile send off up to now by Latin artists to fuse charity with celebrity, are expected to depict a come hearing in the hundreds of thousands. And piece just about participants acknowledged that Latin musical theater artists have lagged behind their U.S. and British people counterparts in altruistic enterprises, "the important thing," Shakira said, "is that we're here today."

Shakira was joined by Catherine Howard Whole wheat flour Buffett, firstborn boy of Rabbit warren Buffett, the world’s richest soul, according to Forbes magazine, and by Mexican telecommunications top executive Glen Gebhard Thin Helú, the world's second base richest, just in front of Circular Gates. Both hands announced they would increase their support of baby development and related programs through and through their personal foundations, Slim pledging $110 meg and Buffett $85 million. "One of the biggest problems anyplace in the globe . . . is the absorption of wealth, which creates a disruption of those wHO hold it and those world Health Organization don't get it," said Buffett, whose origination has given tens of millions of dollars to sociable programs in Mexico and Exchange America. "We experience those problems at home. But Mexico in spades has that challenge."

In a grim coincidence, on Th came an echo from a not-so-distant era when Latin American artists world Health Organization spoke up roughly poverty and sociable inequality took their lives in their custody. In Chile, a try announced the remnant of his investigation into the brutal mutilate of revered kinfolk singer Master Jara, a leader of Latin America's "freshly song" ethnic music crusade. Jara was arrested after the 1973 putsch lED by Gen. Augusto Pinochet and, according to lawcourt records, was tortured in front being machine-gunned to death.

The judge's determination to charge only when 1 soul in the caseful, a retired regular army colonel, was met with discouragement by Jara's attorney and widow woman, world Health Organization said they would invoke. driven resistance or hounded into deportee

During the shadow times when internecine wars raged and dictators of various political grade insignia presided all over much of Latin US, Argentine novelists, Brazilian liberal rock musicians, Salvadorian poets and many others suffered similar fates or were driven resistance.

Even today, with many countries enjoying booming economies and comparatively stable democracies, pickings a stand on a political or mixer issue is a rarer, and dicier, act for Latin performers than for Hollywood stars or john Rock gods such as Sir David Bruce Springsteen or U2's Bono (though the Dixie Chicks might experience a different idea).

Today's concerts ar being staged by the not-for-profit organisation Unfortunately (América Latina en Acción Solidaria), which was founded a twelvemonth and a half ago in Panama Metropolis. Unfortunately (the Spanish people countersign substance "wings") is the first gear Latin American organisation to wreak together so many prominent artists and financial impresarios behindhand a 1 causal agent, early puerility evolution assistance.

Jorge Ramos, the longtime lynchpin of Miami-based Noticiero Univision, the tidings air division of the Univision video network, in a telephone interview called Unluckily "unprecedented" in Latin America.

"In the yesteryear, completely these efforts to help the poor people were very nationalistic, and male-dominated," Ramos said. Regrettably is exhibit that "young multitude and artists" are unification crossways subject and ideological borders and "non expecting politicians to decide their future. They're pickings control of their own future."

Jorge RamosThe supporting of Slenderize, Buffett and another deep-pocketed Unluckily angel, Emilio Azcárraga Jean, chief administrator of the Grupo Televisa amusement company, testifies to the growing pull that Latin America's transcription artists cause with the region's movers and united Society of Believers in Christ's Second Appearing. In previous generations, novelists such as the Peruvian Mario Vargas Llosa and Shakira's fellow Colombian, Gabriel García Márquez (ALAS' honorary president), were the nearly influential cultural figures. Today's pop up artists have taken their place.

Sort of than bringing up money or award grants, Alas is encouraging donations and volunteer support for existing nonprofits. "People ar condemned to poverty because there are no exits, or choices," Shakira said. "And children wHO don't get an opportunity end up as adults organism involved with things that they ne'er imagined they would be doing in the number one piazza, like dose trafficking or being recruited into malefactor groups."

Today's generation of Spanish-speaking stars isn't the first base to take office in charitable endeavors. Romantic crooners such as Julio Julio Iglesias and José José and Cuban salsa queen Celia Cruz have got been known for their philanthropic activities.

Just roughly young artists ar proving to be as outspoken as their predecessors. The Colombian pop singer-songwriter Juanes, sometimes called the Bono of Latin America, performed at the Alfred Nobel Peace Award ceremonies in December, assists mine victims through his Mi Sangre Foundation and in his music on a regular basis addresses the human bell of "narco-political" fierceness. Ramos said that Latin America's whitney Young musical theater artists besides are "break barriers in philanthropy" by persuading to a greater extent members of their countries' privileged elites to function with their wealth for good causes.

"Rich people classes in Latin USA ar not on the dot Saint Nicholas Claus," he said, adding that just about earn their wealth not only through hard sour only as well through "government activity connections, corruption and monopolies."

It crataegus laevigata need a balancing do to maintain support from figures like Melt off and Azcárraga, whose companies have been targets of complaints that they ar quasi-monopolies. Merely, Ramos said,"these artists feel protected because they're doing well financially and they're very well known, just too because they have the means to face those in big businessman and to make them do things."

reed.johnson@latimes.com






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Mallku De Los Andes

   
Artist: Mallku De Los Andes

   Genre(s): 
Latin
   

---

Discography:


   
 On The Wings Of The Condor

   Year: 1999   
Tracks: 7

---

 





Reid, Sharp, Torn

Richie Santana

   
Artist: Richie Santana

   Genre(s): 
House
   

---

Discography:


   
 Drums Control

   Year: 2007   
Tracks: 1

---

Enchantment producer and DJ Richie Santana has remixed for Gloria Estefan and Solar Gemini the Twins. In 2000 he released 2 albums, Don't Be Alarmed and Spell Revolution, respectively.

Sangeetha Shankar

   
Artist: Sangeetha Shankar

   Genre(s): 
Reggae
   

---

Discography:


   
 Aasha

   Year: 2005   
Tracks: 5

---

 





Tom Cruise tells Oprah he wants more challenges

Cowell reveals suicidal teenage years

Cowell reveals suicidal teenage years

'American Idol' judge Herbert Alexander Simon Cowell has spoken about his teenage eld, saying that he felt up suicidal when he was younger.
The headliner told Parade that he hated schooling and feared that his life would not draw better.
He said: "I was constantly bored. I didn't like the rules and I didn't like discipline."
"So when soul said to me, 'These ar the best years of your life', I actually sentiment almost jumping off a bridge."
"I was wish, 'If it gets any worse than this I'm done', because I hated school and I hated my life."




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Dax Riders

   
Artist: Dax Riders

   Genre(s): 
Other
   

---

Discography:


   
 Back in Town

   Year:    
Tracks: 14

---

French electronica getup Dax Riders (named later the Honda Dax ST-70 motorbike) burst into the local scene in 1994 with the release of "Quicker Than a Dax." Cédric Azencoth aka Bad Ced, known for promoting the starting time Theater Political party of Genus Paris in 1991, teamed up with Baron Olivier of Birghton Ruel aka Daxman, wHO began performing in a glam/rock band and then turned into hip-hop. Argentine self-taught multi-instrumentalist Nicolas Berger-Vachon (max Born 1975) aka Erman united them in 1999. That saame year the terzetto released their debut record album, Dax. Backintown followed in 2001, including the contact bingle "People," as well featured in Laissons Lucie Faire's soundtrack.





Robert Michaels